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Naratriptan hydrochloride
CAS No. 143388-64-1
Naratriptan hydrochloride( Naratriptan HCl | Amerge | Naramig | GR-85548A )
Catalog No. M18015 CAS No. 143388-64-1
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 39 | In Stock |
|
| 25MG | 73 | In Stock |
|
| 50MG | 122 | In Stock |
|
| 100MG | 215 | In Stock |
|
| 200MG | 268 | In Stock |
|
| 500MG | 442 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNaratriptan hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionNaratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property.
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DescriptionNaratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
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In Vitro——
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In Vivo——
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SynonymsNaratriptan HCl | Amerge | Naramig | GR-85548A
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PathwayOthers
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TargetOther Targets
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Recptor5-HT1
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number143388-64-1
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Formula Weight371.93
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Molecular FormulaC17H25N3O2S·HCl
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 35 mg/mL; 94.10 mM
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SMILESCNS(=O)(=O)CCc1cc2c(cc1)[nH]cc2C1CCN(CC1)C.Cl
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Chemical NameN-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sattar M, Hadgraft J, Lane ME.Int J Pharm. 2015 Sep 30;493(1-2):146-51.
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